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InChi: InChI=1S/C26H24ClN3O3
high affinity histamine H1-receptor-selective antagonist with Ki of 1
11(3):1039-1044
Smiles: CC1=C(/C=C2/C3=CC(F)=CC=C3NC/2=O)NC(C)=C1C(=O)NCCN1CCCC1
Epub 2009 Sep 10
Bendamustine Hydrochloride ntan Hydrochloride InChi: InChI=1S/C26H24ClN3O3Bendamustine is a bifunctional mechlorethamine derivative with alkylator and antimetabolite activities. Bendamustine possesses three active moieties: an alkylating group; a benzimidazole ring, which may act as a purine analogue; and a butyric acid side chain. Although its exact mechanism of action is unknown, this agent appears to act primarily as an alkylator. Bendamustine metabolites alkylate and crosslink macromolecules, resulting in DNA, RNA and
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