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on trabecular meshwork and Schlemm's canal endothelial cells
in cells transfected with the empty plasmid which has no CYP1B1 gene and therefore cannot express CYP1B1 protein
Perifosine strongly reduces phosphorylation levels of Akt and extracellular signal-regulated kinase (Erk) 1/2
Ruboxistaurin attenuates diabetic nephropathy via modulation of TGF-β1/Smad and GRAP pathways
2016 Dec 6
PF-06380101 CP 171 on trabecular meshwork and Schlemm'sPF 06380101 is a proprietary microtubule inhibitor (MTI). Product information CAS Number: 1436391 86 4 Molecular Weight: 743. 01 Formula: C39H62N6O6S Chemical Name: (2S) 2 (2 amino 2 methylpropanamido) N [(3R,4S,5S) 3 methoxy 1 [(2S) 2 [(1R,2R) 1 methoxy 2 methyl 2 {[(1S) 2 phenyl 1 (1,3 thiazol 2 yl)ethyl]carbamoyl}ethyl]pyrrolidin 1 yl] 5 methyl 1 oxoheptan 4 yl] N,3 dimethylbutanamide Smiles:
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