JTE-607 394Methyl Atorvastatin hemicalcium DMT1 blocker 2 can block

DMT1 blocker 2 can block iron uptake by enterocytes in vivo

InChiKey: YHGSTSNEOJUIRN-UHFFFAOYSA-N

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CAS Number: 425386-60-3

InChi: InChI=1S/C17H15ClO3/c1-20-14-7-3-12(4-8-14)16(11-19)17(18)13-5-9-15(21-2)10-6-13/h3-11H

JTE-607 394Methyl Atorvastatin hemicalcium DMT1 blocker 2 can blockJTE 607, a highly selective inflammatory cytokine synthesis inhibitor, protects from endotoxin shock in mice. JTE 607 inhibits inflammatory cytokine production, including TNF , IL 1, IL 6, IL 8 and IL 10, from LPS stimulated human PBMCs, with IC50s of 11, 5. 9, 8. 8, 7. 3 and 9. 1 nM, respectively. Cleavage and Polyadenylation Specificity Factor 3 (CPSF3) is the target of JTE 607. Product information CAS Number: 188791 09 5 Molecular Weight: 597. 36