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UT-34 Catalog No.:M25039-C Formula: C22H32BrNO5

SKU: 29140977353

4.5
USD120.00 USD169.00

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Description

Formula: C22H32BrNO5

InChi: InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9

Smiles: C[C@]12CC[C@H]3[C@H]([C@@H]1[C@@H]1C[C@@H]1[C@]12CCC(=O)O1)[C@H]1C[C@H]1C1=CC(=O)CC[C@@]13C

) effectively inhibits the FLT3 pathway and significant inhibits tumor growth

bisBenzimide H 33258

UT-34 Catalog No.:M25039-C Formula: C22H32BrNO5UT 34 is a potent, selective and orally active second generation pan androgen receptor (AR) antagonist and degrader with IC50s of 211. 7 nM, 262. 4 nM and 215. 7 nM for wild type, F876L and W741L AR, respectively. UT 34 binds to ligand binding domain (LBD) and function 1 (AF 1) domains and requires ubiquitin proteasome pathway to degrade the AR. UT 34 has anti prostate cancer efficacy. Product information CAS Number: 2168525 92 4 Molecular Weight:

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