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Urocortin II, human fenozide 49(88)33-86)31-38-58(48)65(104)60-59(63(38)102)62(101)37-6-5-8-47(113-2)57(37)64(60)103)79-69(108)43(26-52(92)93)82-71(110)45(28-54(96)97)84-72(111)46(29-55(98)99)83-70(109)44(27-53(94)95)81-66(105)39(7-3-4-14-74)78-67(106)41(24-35-9-11-36(87)12-10-35)80-68(107)42(25-51(90)91)77-50(89)13-16-114-18-20-116-22-23-117-21-19-115-17-15-76-85-75/h5-6

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Description

49(88)33-86)31-38-58(48)65(104)60-59(63(38)102)62(101)37-6-5-8-47(113-2)57(37)64(60)103)79-69(108)43(26-52(92)93)82-71(110)45(28-54(96)97)84-72(111)46(29-55(98)99)83-70(109)44(27-53(94)95)81-66(105)39(7-3-4-14-74)78-67(106)41(24-35-9-11-36(87)12-10-35)80-68(107)42(25-51(90)91)77-50(89)13-16-114-18-20-116-22-23-117-21-19-115-17-15-76-85-75/h5-6

This was accompanied by NF-κB pathway suppression

Chemical Name: 3-[(1-{[1-({1-[(1-{[1-({1-[(5-amino-1-{[1-({1-[(1-{[1-({5-amino-1-[(5-amino-1-{[1-({1-[(1-{[1-({1-[(5-amino-1-{[1-({5-amino-1-[(4-carbamimidamido-1-{[1-carbamoyl-2-(4-hydroxyphenyl)ethyl]carbamoyl}butyl)carbamoyl]pentyl}carbamoyl)-2-carbamoylethyl]carbamoyl}pentyl)carbamoyl]-2-methylbutyl}carbamoyl)-2-hydroxyethyl]carbamoyl}-3-carbamoylpropyl)carbamoyl]-3-methylbutyl}carbamoyl)-2-(4-hydroxyphenyl)ethyl]carbamoyl}pentyl)carbamoyl]pentyl}carbamoyl)ethyl]carbamoyl}ethyl)carbamoyl]-2-methylpropyl}carbamoyl)-3-carbamoylpropyl]carbamoyl}pentyl)carbamoyl]-4-carbamimidamidobutyl}carbamoyl)-3-methylbutyl]carbamoyl}-4-carbamimidamidobutyl)carbamoyl]-2-hydroxypropyl}carbamoyl)-2-(4-hydroxyphenyl)ethyl]carbamoyl}-2-carbamoylethyl)carbamoyl]-3-[2-(2-{2-[2-(2-{2-[2-amino-3-(1H-imidazol-4-yl)propanamido]-3-hydroxypropanamido}-3-carboxypropanamido)propanamido]-3-methylbutanamido}-3-phenylpropanamido)-3-hydroxybutanamido]propanoic acid

5% is the 13-cis and less than 1% is the 9-cis with 94% being all-trans

CAS Number: 2170608-82-7

Urocortin II, human fenozide 49(88)33-86)31-38-58(48)65(104)60-59(63(38)102)62(101)37-6-5-8-47(113-2)57(37)64(60)103)79-69(108)43(26-52(92)93)82-71(110)45(28-54(96)97)84-72(111)46(29-55(98)99)83-70(109)44(27-53(94)95)81-66(105)39(7-3-4-14-74)78-67(106)41(24-35-9-11-36(87)12-10-35)80-68(107)42(25-51(90)91)77-50(89)13-16-114-18-20-116-22-23-117-21-19-115-17-15-76-85-75/h5-6Urocortin II (human) is a selective endogenous peptide agonist of type 2 corticotropin releasing factor (CRF2) receptor. For investigating the role of the CRF (2) receptor in ingestive behavior. Product information Molecular Weight: 4450. 22 Formula: C194H339N63O54S Chemical Name: Urocortin II, human Smiles:

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