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while values in BHK cells were 0
Smiles: C(NC1=NC2=CC=CC=C2C(NCC2C=CC=CC=2)=N1)C1C=CC=CC=1
CAS Number: 1093978-89-2
InChiKey: MALFODICFSIXPO-KFKQDBFTSA-N
It is more accurately a hydroxyethylrutoside
Ruxolitinib sulfate - CAS# 1092939-16-6 alog 2 while values in BHK cellsRuxolitinib sulfate is the first potent, selective JAK1 2 inhibitor to enter the clinic with IC50s of 3. 3 nM 2. 8 nM, and has > 130 fold selectivity for JAK1 2 versus JAK3. Ruxolitinib potently and selectively inhibits JAK2V617F mediated signaling and proliferation, markedly increases apoptosis in a dose dependent manner, and at 64 nM results in a doubling of cells with depolarized mitochondria in Ba F3 cells. Ruxolitinib demonstrates remarkable
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