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Smiles: CN1C(C=CC(=O)C2=CC(F)=CC=C2)=CC=C1C=CC(=O)NO
flow cytometric analysis shows that there are significantly more MYHlo + cells in IWP-4 treated cultures (P<0
and anchorage-independent colony formation in soft agar
It referred to as an uncoupling agent because it disrupts ATP synthesis by transporting hydrogen ions through a cell membrane before they can be used to provide the energy for oxidative phosphorylation
2015 Jan 12
K-252a - CAS# 99533-80-9 60261 Smiles: CN1C(C=CC(=O)C2=CC(F)=CC=C2)=CC=C1C=CC(=O)NOK 252a, CAS No. 99533 80 9, also known as SF 2370, is an alkaloid isolated from Nocardiopisis bacteria. This staurosporine analog is a highly potent cell permeable inhibitor of CaM kinase and phosphorylase kinase (IC50 = 1. 8 and 1. 7 nmol L, respectively). At higher concentrations it is also an efficient inhibitor of serine threonine protein kinases (IC50 of 10 to 30 nmol L). Product information CAS Number: 99533 80 9 Molecular Weight: 467. 47
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