PZM21 - CAS# 1997387-43-5 chloride hydrate(x) CC(=O)OCC1CS[C@H]2[C@@H](NC(=O)CCC[C@H](N)C([O-])=O)C(=O)N2C=1C(O)=O

CC(=O)OCC1CS[C@H]2[C@@H](NC(=O)CCC[C@H](N)C([O-])=O)C(=O)N2C=1C(O)=O

Dragnev KH

It has a half-life in circulation of around 30 seconds

and neurodegenerative diseases

but not to vascular smooth muscle and endothelial cells

PZM21 - CAS# 1997387-43-5 chloride hydrate(x) CC(=O)OCC1CS[C@H]2[C@@H](NC(=O)CCC[C@H](N)C([O-])=O)C(=O)N2C=1C(O)=OPZM21 is a potent Gi activator with exceptional selectivity for OR and minimal arrestin 2 recruitment. PZM21 is an experimental opioid analgesic drug that is being researched for the treatment of pain. It is a functionally selective opioid receptor agonist which produces opioid receptor mediated G protein signaling, with potency and efficacy similar to morphine, but with less arrestin 2 recruitment. In tests on mice, PZM21 was slightly less potent