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Peroxisome proliferator-activated receptor-gamma1 is dephosphorylated and degraded during Bay11-7085-induced synovial fibroblast apoptosis
as a potent and selective agonist at the peripheral benzodiazepine receptor
Formula: C17H20N2O2
Roberta Costi
InChi: InChI=1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17
Pimavanserin - CAS# 706779-91-1 Size:Solid 10 mg Peroxisome proliferator-activated receptor-gamma1 is dephosphorylatedPimavanserin, also known as ACP 103, is an inverse agonist on the serotonin receptor subtype 5 HT2A, with 40x selectivity over 5 HT2C, and no significant affinity or activity at 5 HT2B or dopamine receptors. Pimavanserin is a novel drug candidate for Parkinson's psychosis. Parkinson's disease psychosis (PDP) is a condition that may develop in up to 60 % of Parkinson's patients, and is a major reason for nursing home placement for those affected.
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