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which may lead to a reduction in cellular proliferation of cancer cells expressing DNA-PK and TOR
It has excellent selectivity against human DUBs
MI-2 was nontoxic to mice
54(41):12020-4
Formula: C16H16N6O
TRIM24-C34 - BRPF1B/TRIM24 Dual Inhibitor. CAS# 1242907-48-7 ry of Histone Demethylase which may lead to aTRIM24 C34, CAS No. 1242907 48 7, is a potent, selective and cell permeable BRPF1B and TRIM24 dual inhibitor. TRIM24 C34 binds to bromodomain BRPF1B with a Kd of 137 nM, and the transcriptional regulator TRIM24 (also an E3 ubiquitin ligase) with a Kd of 222 nM. It has very good selectivity against other 45 bromodomains. Cellular activity of TRIM24 C34 was demonstrated using FRAP assays as well as cell viability data. It showed no significant
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