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382 μM for A2780 cell lines)
EW-7197 Hydrochloride
InChi: InChI=1S/C12H20O2/c1-8(13)14-10-7-9-5-6-12(10
Smiles: CC1=CC(=CC=C1CCC(O)=O)OCC1=NC(=CS1)C1=CC=CC=C1Cl
PubMed PMID: 25279148
Compound E Catalog No.:M13053-2 382 μM for A2780 cellCompound E is a secretase inhibitor. Compound E bloks amyloid(40), amyloid(42), and Notch secretase cleavage with IC50s of 0. 24, 0. 37, 0. 32 nM, respectively. Product information CAS Number: 209986 17 4 Molecular Weight: 490. 50 Formula: C27H24F2N4O3 Chemical Name: (2S) 2 [2 (3,5 difluorophenyl)acetamido] N [(3S) 1 methyl 2 oxo 5 phenyl 2,3 dihydro 1H 1,4 benzodiazepin 3 yl]propanamide Smiles: