SAR-260301 C BET Degrader-1 InChi: InChI=1S/C41H47Cl2NO6/c1-41-21-20-34-33-17-15-32(49-40(47)29-7-3-2-4-8-29)26-30(33)12-16-35(34)36(41)18-19-37(41)50-39(46)27-48-38(45)9-5-6-28-10-13-31(14-11-28)44(24-22-42)25-23-43/h2-4

InChi: InChI=1S/C41H47Cl2NO6/c1-41-21-20-34-33-17-15-32(49-40(47)29-7-3-2-4-8-29)26-30(33)12-16-35(34)36(41)18-19-37(41)50-39(46)27-48-38(45)9-5-6-28-10-13-31(14-11-28)44(24-22-42)25-23-43/h2-4

and 30 mg/kg) compare to vehicle control over the 60 min test

2)10-17(24)19(14)20/h9

3R)-3-amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoyl]oxy}ethoxy)ethoxy]ethyl}carbamoyl)methoxy]imino}-2

thus retaining the nontaster FVB phenotype

SAR-260301 C BET Degrader-1 InChi: InChI=1S/C41H47Cl2NO6/c1-41-21-20-34-33-17-15-32(49-40(47)29-7-3-2-4-8-29)26-30(33)12-16-35(34)36(41)18-19-37(41)50-39(46)27-48-38(45)9-5-6-28-10-13-31(14-11-28)44(24-22-42)25-23-43/h2-4SAR 260301 is an orally available and selective PI3K inhibitor with an IC50 of 23 nM. Product information CAS Number: 1260612 13 2 Molecular Weight: 354. 40 Formula: C19H22N4O3 Chemical Name: 2 {2 [(2S) 2 methyl 2,3 dihydro 1H indol 1 yl] 2 oxoethyl} 6 (morpholin 4 yl) 1,4 dihydropyrimidin 4 one Smiles: C[C@H]1CC2C=CC=CC=2N1C(=O)CC1NC(=CC(=O)N=1)N1CCOCC1 InChiKey: UAXHPOBBKRWJGA ZDUSSCGKSA N InChi: InChI=1S C19H22N4O3 c1 13 10 14 4 2 3 5