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(Rac)-Calpain Inhibitor XII inib bromide 5)1(6)7/h12-13

SKU: 25841508155

4.5
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Description

5)1(6)7/h12-13

Chemical Name: 2-[4-(1-{1-[7-fluoro-3-(1-methyl-1H-pyrazol-4-yl)quinolin-6-yl]ethyl}-1H-[1

RITA (1 μM) stabilizes p53 by inhibiting p53/E6AP interaction

and 10-fold selective for the α2Areceptor relative to the α2C-receptor

The protection of omtriptolide against AKI is associated with a decrease in p-ERK and is independent of MKP-1 and proinflammatory cytokines

(Rac)-Calpain Inhibitor XII inib bromide 5)1(6)7/h12-13(Rac) Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I ( calpain, Ki=19 nM). (Rac) Calpain Inhibitor XII has lower affinities for calpain II (m calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac) Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. Product information CAS Number: 181769 57 3

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