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Delgocitinib inhibits radiographic and histological changes of bone destruction and cartilage destruction
OC(=O)C1CCNCC=1
Chemical Name: 2-({4-[1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline
Cenicriviroc Mesylate100 BID
InChi: InChI=1S/C81H140N20O23/c1-16-45(12)65(98-72(114)54(38-60(85)105)92-74(116)58-26-22-34-101(58)80(122)56(37-42(6)7)95-75(117)63(43(8)9)96-61(106)39-86-48(15)103)77(119)90-51(27-29-59(84)104)68(110)87-46(13)67(109)97-64(44(10)11)76(118)93-53(35-40(2)3)71(113)94-55(36-41(4)5)79(121)100-33-21-25-57(100)73(115)89-49(23-17-19-31-82)69(111)88-50(24-18-20-32-83)70(112)99-66(47(14)102)78(120)91-52(81(123)124)28-30-62(107)108/h40-47
Syk Inhibitor II P 14 Delgocitinib inhibits radiographic and histologicalSyk Inhibitor II is a potent, high selective and ATP competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II inhibits 5 HT release from RBL cells with an IC50 of 460 nM. Syk Inhibitor II shows less potent against other kinases and has anti allergic effect. Product information CAS Number: 726695 51 8 Molecular Weight: 340. 30 Formula: C14H15F3N6O Chemical Name: 2 [(2 aminoethyl)amino] 4 {[3 (trifluoromethyl)phenyl]amino}pyrimidine 5
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