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ICA-105665 Catalog No.:M15782-C Research Article Volume 2017

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Description

Research Article Volume 2017

Intracerebroventricularly administered Orexin-A (30 μg/10 μL) blocks the vasopressin (VP) level increase induced by either histamine or 2

Chemical Name: 2-({[(2-oxothiolan-3-yl)carbamoyl]methyl}sulfanyl)acetic acid

Epub 2014 Feb 27

ATP-competitive inhibitor of protein kinase A (PKA)

ICA-105665 Catalog No.:M15782-C Research Article Volume 2017ICA 105665 (PF 04895162) is a potent and orally active neuronal Kv7. 2 7. 3 and Kv7. 3 7. 5 potassium channels opener. ICA 105665 inhibits liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 M). ICA 105665 can penetrate the blood brain barrier and has antiseizure effects. Product information Molecular Weight: 355. 34 Formula: C19H15F2N3O2 Chemical Name: N (2 cyclopropyl 7 fluoro 4 oxo 3,4 dihydroquinazolin 3 yl) 2

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