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RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency
Formula: C21H25N3O6
1-diyl) bis(1-((S)-2-(3
30)6/h14-15
2173992-60-2
WEHI-345 - CAS# 1354825-58-3 size:10mg solid RS-1 enhances CRISPR/Cas9- and TALEN-mediatedWEHI 345, CAS No. 1354825 58 3, is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production. WEHI 345 delays RIPK2 ubiquitylation and NF B activation downstream of NOD engagement. Despite only delaying NF B activation on NOD stimulation, WEHI 345 prevents cytokine production in vitro and in vivo and ameliorates experimental autoimmune encephalomyelitis in mice. Product information CAS
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