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is a potent and selective antagonist of the G protein-coupled receptor identified as EBI2 (GPR183) (IC50 values are 11 and 15 nM for human and mouse EBI2 receptors
but not lower doses or vehicle
CAS Number: 434-22-0
org/wiki/Deguelin)
23(4):477-88
Lycorine - CAS# 476-28-8 2171 is a potent and selectiveLycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15. 24 nM. Lycorine downregulates the SCAP protein level without changing its transcription. Lycorine is also a melanoma vasculogenic inhibitor. Lycorine can be used for the study of prostate cancer and metabolic diseases. Product information CAS Number: 476 28 8 Molecular Weight: 287. 31 Formula: C16H17NO4
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