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TCID - Ubiquitin C-terminal Hydrolase-L3 (UCH-L3) Inhibitor. CAS# 30675-13-9 0274 1597403-47-8

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Description

1597403-47-8

LY294002 could be dosed to the mice by IP administration at 100 mg/kg once day

(2004) J Med Chem

Smiles: CN1CCC[C@@H](C1)COC1=CC(=CC2CN(CCOC=21)C(=O)CC)C1=CC(OC)=C(C=C1)OC

RKI-1447 is a Type I kinase inhibitor that binds the ATP binding site through interactions with the hinge region and the DFG motif

TCID - Ubiquitin C-terminal Hydrolase-L3 (UCH-L3) Inhibitor. CAS# 30675-13-9 0274 1597403-47-8TCID, CAS No. 30675 13 9, is a novel potent and selective inhibitor of ubiquitin C terminal hydrolase L3 (UCH L3) with an IC50 ~0. 6 M. It has ~125 fold greater selectivity over UCH L1 (ubiquitin C terminal hydrolase L1, IC50 ~75 M). TCID can diminish glycine transporter GlyT2 ubiquitination in brain stem and spinal cord primary neurons. Product information CAS Number: 30675 13 9 Molecular Weight: 283. 92 Formula: C9H2Cl4O2 Chemical Name: 4,5,6,7

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