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Molecular Weight: 348
3T3 fibroblasts
InChi: InChI=1S/C21H22N2O4S/c1-28(25
It can inhibit EGFR and Her2 phosphorylation
Methoxy-X04 retains in vitro binding affinity for amyloid beta (Abeta) fibrils (Ki = 26
LLY-507 - Protein-lysine Methyltransferase SMYD2 Inhibitor. CAS# 1793053-37-8 Asn-PAB-PNP Molecular Weight: 348LLY 507, CAS No. 1793053 37 8, is a potent, selective and cell permeable protein lysine methyltransferase SMYD2 inhibitor with IC50 <15 nM. It binds in the substrate peptide binding pocket. It has >100 fold selectivity over other methyltransferases and other non epigenetic targets. LLY 507 has been shown to inhibit p53K370 monomethylation in cells with an IC50 ~600 nM. It inhibited the proliferation of several esophageal, liver, and breast cancer cell
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