Gatifloxacin sesquihydrate opropane-F When administered systemically to mice

When administered systemically to mice

InChiKey: YYNXYOVXFJJJHD-OCIHUODESA-N

a derivative of Raloxifene

promotes breast cancer cells to undergo apoptosis through activating p53 and inducing expression of proapoptotic genes

728865-23-4

Gatifloxacin sesquihydrate opropane-F When administered systemically to miceGatifloxacin sesquihydrate (AM 1155; BMS 206584; PD135432) is a potent fluoroquinolone antibiotic with broad spectrum antibacterial activity. Gatifloxacin sesquihydrate inhibits bacterial type II topoisomerases (IC50=13. 8 g ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0. 109 g ml). Gatifloxacin sesquihydrate can be used to treat bacterial conjunctivitis in vivo. Product information CAS Number: 180200 66 2 Molecular Weight: 402.