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Konopleva M
WS 3 is an agonist of TRPM8 with an EC50 of 3
but can completely inhibit the proliferation of a broad panel of tumor cells at low micromolar concentrations (5-15 μM)
The compound was selective versus a panel of greater than 200 additional receptor tyrosine kinase (RTKs)
TC-S 7003 is an inhibitor of lymphocyte specific kinase (Lck)
12S-HHT 1722 Konopleva M12S HHT (12(S) HHTrE) is an enzymatic product of prostaglandin H2 (PGH2) derived from cyclooxygenase (COX) mediated arachidonic acid metabolism. 12S HHT is an endogenous ligand for BLT2 that fully activates BLT2 in vivo. 12S HHT suppresses UV induced IL 6 synthesis in keratinocytes, exerting an anti inflammatory activity. Product information CAS Number: 54397 84 1 Molecular Weight: 280. 40 Formula: C17H28O3 Chemical Name: (5Z,8E,10E,12S) 12