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LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via H2O2-MAPK activation and up-regulation of death receptors
a benzophenanthridine alkaloid known as an anti-inflammatory agent
Smiles: CC(C)C[C@H]([C@H](O)C(=O)NO)C(=O)N[C@@H](C1=CC=CC=C1)C(=O)OC1CCCC1
Molecular Weight: 449
23)24)27-28-29-30)12-15(18)13-26-17-8-5-11-25-19(17)14-6-3-2-4-7-14/h2-4
MK-0674 macrenal LY303511 enhances TRAIL sensitivity ofMK 0674 is a potent, orally bioavailable and selective cathepsin K inhibitor, with an IC50 of 0. 4 nM, shows 1156, 1465, 11857 and 243 fold selectivity over Cat B, Cat F, Cat L and Cat S. Product information CAS Number: 887781 62 6 Molecular Weight: 527. 50 Formula: C26H27F6N3O2 Chemical Name: (2S) N (1 cyanocyclopropyl) 2 {[(1S) 1 {4' [(1R) 2,2 difluoro 1 hydroxyethyl] [1,1' biphenyl] 4 yl} 2,2,2 trifluoroethyl]amino} 4 fluoro 4 methylpentanamide
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