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It inhibits growth of MCF7a breast cancer cells (IC50 ~1
represents a novel agent for ALK positive anaplastic large cell lymphoma
It is highly selective over related enzymes such as MAO-A/B
1883545-53-6 (2HCl)
10b-trihydroxy-3
1, 4-DPCA - Prolyl 4-hydroxylase (P4H) Inhibitor. CAS# 331830-20-7 Catalog No.:M60288-10S It inhibits growth of MCF7a1, 4 DPCA, CAS No. 331830 20 7, is a selective and cell permeable prolyl 4 hydroxylase (P4H) inhibitor. It inhibits prolyl4 hydroxylase, an oxygen sensing enzyme that targets the pro angiogenic factor HIF 1 for destruction upon hydroxylation of a specific proline residue. It also inhibits asparaginyl hydroxylase factor inhibiting HIF (FIH) and is useful for controlling excess collagen deposition in pathological fibrosis. Product information CAS