Pay in 4 interest-free payments of $23.75 Learn more
Ships within 48 hours · Estimated delivery Aug 2 - Aug 7
and a 20-fold decrease in potency as a Cdk antagonist
66-49+/t44-
Myocardial remodeling in diabetic cardiomyopathy associated with cardiac mast cell activation
Sortin1 is a sorting inhibitor
801315-14-0 (HCl)
BI-D1870 - CAS# 501437-28-1 Catalog No.:M11147-2 and a 20-fold decrease inBI D1870 is a potent and specific RSK inhibitor (the p90 ribosomal S6 kinase), which inhibits RSK1, RSK2, RSK3 and RSK4 in vitro with an IC50 of 1030 nM. BI D1870 exhibited a dose responsive antiproliferative effect on OSCC cells with relative sparing of normal human oral keratinocytes. The compound inhibited the downstream RSK target YB 1 and caused apoptosis. In addition, BI D1870 also induced G2 M arrest by modulating the expression of p21 and
US$ 15.95
US$ 29.88
US$ 18.75
US$ 33.95
US$ 25.95
US$ 129.40