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Williams VC
CAS Number: 34839-70-8
Ann Neurol
mercaptopurine metabolites 6-thioguanosine-5'-phosphate (6-thioGMP) and 6-thioinosine (T-IMP) inhibit nucleotide interconversions and de novo purine synthesis
Resatorvid
Xanthatin vanone G Williams VCXanthatin is isolated from Xanthium strumarium leaves. Xanthatin exhibits strong antitumor activities against a variety of cancer cells through apoptosis persuasion and shows anti inflammatory activities by inhibiting PGE2 synthesis and 5 lipoxygenase activity. Xanthatin is a potent and orally active inhibitor of VEGFR2 kinase activity with an IC50 of 3. 8 M and prominently blocks the phosphorylation of VEGFR2 at Tyr951 site. Xanthatin inhibits
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