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inhibits cytokine-induced vascular cell adhesion molecule-1 expression and activity in human endothelial cells
Clementi ME
CAS Number: 2349372-98-9
PubMed PMID: 25847957
01 nM-100 μM) robustly stimulates inositol phosphate (IP) accumulation and Ca2+ mobilization in CHO-hM5 cells
Abrocitinib Size:Contact [email protected] for quotation inhibits cytokine-induced vascular cell adhesionAbrocitinib (PF 04965842) is a potent, orally active and selective JAK1 inhibitor, with IC50s of 29 and 803 nM for JAK1 and JAK2, respectively. Abrocitinib (PF 04965842) exhibits less active effect on TYK2 (IC50, 1. 253 M), and inhibits phosphorylation of STAT1, STAT3 and STAT5 after stimulation. Effective in autoimmune disease. Product information CAS Number: 1622902 68 4 Molecular Weight: 323. 41 Formula: C14H21N5O2S Chemical Name: N [(1s,3s) 3
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