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Caspase-3/7 Inhibitor I Catalog No.:M23015-C 3-thiazole-4-carboxamide hydrochloride

SKU: 15345076010

4.4
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Description

3-thiazole-4-carboxamide hydrochloride

In a model of the human polarized airway epithelium

12-pentaene-5-carboxamide

TCO-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs

3)4/h5-21H2

Caspase-3/7 Inhibitor I Catalog No.:M23015-C 3-thiazole-4-carboxamide hydrochlorideCaspase 3 7 inbibitor I is a potent, reversible, isatin sulfonamide based inhibitor of caspase 3 (KI(app) = 60 nM) and caspase 7 (KI(app) = 170 nM). Is a weaker inhibitor of caspase 9 (Ki(app) = 3. 1 mM). It Has only a trivial effect (Ki(app) >25 mM) on the activities of caspase 1, caspase 2, caspase 4, caspase 6, and caspase 8. It has been shown to inhibit apoptosis in camptothecin treated Jurkat cells (IC50 ~50 M). Also it has been reported to

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