Tivozanib (hydrate) Size:Contact [email protected] for quotation 7aS)-4-[(acetyloxy)methyl]-7-hydroxy-1

7aS)-4-[(acetyloxy)methyl]-7-hydroxy-1

1533426-72-0

Chemical Name: (2S)-2-amino-5-[(E)-N''-methylcarbamimidamido]pentanoic acid

36)24-8-3-2-4-9-24

AZD3229 is a potent

Tivozanib (hydrate) Size:Contact [email protected] for quotation 7aS)-4-[(acetyloxy)methyl]-7-hydroxy-1Tivozanib, also known as AV 951 and KRN 951, is an orally active, ATP competitive, small molecule, quinoline urea derivative. Tivozanib is a pan VEGFR tyrosine kinase inhibitor. In vitro: Tivozanib markedly inhibited the ligand induced phosphorylation of VEGFR1\2 and 3 with the IC50 value of 30 nM\6. 5 nM and 15 nM, respectively. Tivozanib also exihibited inhibitory effects on PDGFR and c Ki with the IC50 value of 1. 72 and 1. 63 nmol L, respectively.