Pay in 4 interest-free payments of $10.50 Learn more
Ships within 48 hours · Estimated delivery Aug 2 - Aug 7
22)23/h1-2
24)21-7-2-8-22(10-9-21)30(25
InChi: InChI=1S/C19H17F6N7O/c1-17(2
2(6):408-18
Smiles: CC1C=CC(=CC=1)S(=O)(=O)OCC(=O)NC1=CC(O)=C(C=C1)C(O)=O
JIB-04 (NSC693627) - Jumonji Histone Demethylase Inhibitor. CAS# 199596-05-9 0156 22)23/h1-2JIB 04 (NSC693627, E isomer), CAS No. 199596 05 9, is a potent, selective and cell permeable Jumonji histone demethylase inhibitor. Unlike the other known inhibitors, JIB 04 is not a competitive inhibitor of a ketoglutarate. It inhibits the demethylase activity of Jumonji enzymes in vitro, with IC50 ~230 nM for JARID1A (KDM5A), ~440 nM for JMJD2A (KDM4A) and JMJD2B (KDM4B), ~340 nM for JMJD2E (KDM2E), and ~1 M for JMJD3 (KDM6B) and JMJD2C (KDM4C). JIB
US$ 2311.50
US$ 819.50
US$ 19.99
US$ 2304.50
US$ 2399.50
US$ 862.00
US$ 1444.50
US$ 20.00