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2 and 10 mg/kg in elevated plus maze (male C57Bl/6 mice)
Smiles: CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CC1C=CC(O)=CC=1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1C=CC(O)=CC=1)C(=O)N[C@@H](CC1C=CC(O)=CC=1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC1C=CC(O)=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1C=CC(O)=CC=1)C(N)=O
DNA fragmentation
24-72 hours) shows a relationship between cell cycle blocking activity and growth inhibition in breast cancer cells
InChiKey: CCZYBOXFQXWQIF-WFGJKAKNSA-N
N-(m-PEG4)-N'-(PEG2-acid)-Cy5 Size:Contact [email protected] for quotation 2 and 10 mg/kg inN (m PEG4) N' (PEG2 acid) Cy5 is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2107273 24 3 Molecular Weight: 741. 35 Formula: C41H57ClN2O8 Chemical Name: 2 [5 (1 {2 [2 (2 carboxyethoxy)ethoxy]ethyl} 3,3 dimethyl 2,3 dihydro 1H indol 2 ylidene)penta 1,3 dien 1 yl] 3,3 dimethyl 1 (2,5,8,11 tetraoxatridecan 13 yl) 3H indol 1 ium chloride Smiles: [Cl ].