NVP-BAG956 - CAS# 853910-02-8 imesulide 1'-biphenyl]-4-yl)oxy)methyl)-4H-1

1'-biphenyl]-4-yl)oxy)methyl)-4H-1

In addition to direct effects on cells of the osteoclast lineage

MLV 19835A

5 nM and 823

7(8):1211-7

NVP-BAG956 - CAS# 853910-02-8 imesulide 1'-biphenyl]-4-yl)oxy)methyl)-4H-1BAG 956, also known as NVP BAG956, is a dual PDK1 and class I PI 3 kinase inhibitor. BAG 956 has been shown to inhibit cellular AKT phosphorylation at Thr308. BAG 956 also blocks cell proliferation and causes arrest in the G1 phase of the cell cycle. BAG 956 has been shown to slow tumor progression in mouse xenograft models. Product information CAS Number: 853910 02 8 Molecular Weight: 427. 50 Formula: C28H21N5 Synonym: BAG 956 Chemical Name: 2 methyl