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6-MSITC) activates Nrf2 and induces phase II enzyme genes but this induction is absent in Nrf2-null mice
3S)-2-amino-3-methylpentanoyl]amino]propanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-5-oxopentanoyl]amino]-4-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S
In radioligand binding assays
Formula: C30H34N4O
InChi: InChI=1S/C18H22N2S
VER-246608 14393 6-MSITC) activates Nrf2 and inducesVER 246608 is a potent and ATP competitive inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50s of 35 nM, 40 nM, 84 nM, and 91 nM for PDK 1, PDK 3, PDK 2, and PDK 4, respectively. Product information CAS Number: 1684386 71 7 Molecular Weight: 552. 96 Formula: C28H23ClF2N4O4 Chemical Name: N [4 (2 chloro 5 methylpyrimidin 4 yl)phenyl] N ({4 [(2,2 difluoroacetamido)methyl]phenyl}methyl) 2,4 dihydroxybenzamide Smiles:
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