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TAK-960 - CAS# 1137868-52-0 Catalog No.:M6675-10 ) is well tolerated

SKU: 27293978507

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Description

) is well tolerated

is a novel dual PI3K/mTOR inhibitor with an IC50 ~1 nM

AR7 is the first small molecule developed to selectively stimulate CMA without affecting macroautophagy

TUG-770 exhibits lower potency on the rodent orthologs (mFFA1

Molecular Weight: 443

TAK-960 - CAS# 1137868-52-0 Catalog No.:M6675-10 ) is well toleratedTAK 960, CAS No. 1137868 52 0, is a n orally available PLK1 inhibitor with potential antineoplastic activity. Polo like kinase 1 inhibitor TAK 960 selectively inhibits PLK1, inducing selective G2 M cell cycle arrest followed by apoptosis in a variety of tumor cells while causing reversible cell cycle arrest at the G1 and G2 stages without apoptosis in normal cells. PLK1 inhibition may result in the inhibition of proliferation in PLK1 overexpressed

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