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GSK1521498 free base (hydrochloride) is being used for the treatment of disorders of compulsive consumption of food
Chemical Name: 2-[(3S)-1-[5-(cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]-3-piperidyl]acetic acid
InChiKey: IUWKNLFTJBHTSD-QXUNDURPSA-N
LPA2 and LPA3 with Ki of 0
enterovirus 71 (EV71) and human rhinovirus (HRV)
PF-5006739 Size:Contact [email protected] for quotation GSK1521498 free base (hydrochloride) isPF 5006739 is a potent and selective inhibitor of CK1 with IC50s of 3. 9 nM and 17. 0 nM, respectively. PF 5006739 is a potential therapeutic agent for a range of psychiatric disorders with low nanomolar in vitro potency for CK1 and high kinome selectivity. PF 5006739 attenuats opioid drug seeking behavior in a rodent operant reinstatement model in animals in a dose dependent manner. PF 5006739 improves glucose tolerance in both diet induced obesity