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Smiles: CCOC(=O)C1=CC(N)=C(C=C1)NC1CCCCC1
Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface
InChiKey: XMYKNCNAZKMVQN-NYYWCZLTSA-N
Baohuoside I is both anti-inflammatory and immunosuppressive
It can inhibit ULK in vitro and block autophagy in cells
Hesperadin C sodium Smiles: CCOC(=O)C1=CC(N)=C(C=C1)NC1CCCCC1Hesperadin is an inhibitor of human Aurora B, which can prevent the phosphorylation of substrate with IC(50) of 40 nM. Growth of cultured bloodstream forms was also sensitive to Hesperadin (IC(50) of 50 nM). Hesperadin blocked nuclear division and cytokinesis but not other aspects of the cell cycle. Consequently, growth arrested cells accumulated multiple kinetoplasts, flagella and nucleoli, similar to the effects of RNAi dependent knockdown of TbAUK1
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