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FASCIN-G2 - Fascin Inhibitor. CAS# 1569076-11-4 yamine 3-²H₇)propan-2-yl]amino}ethyl)-17-oxa-3

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Description

3-²H₇)propan-2-yl]amino}ethyl)-17-oxa-3

CAS Number: 21414-42-6

Smiles: OC1C=CC(=CC=1)NC(=O)C1=CC=CC=C1O

Pfeiffer (DLBCL)

PD173074 also potently inhibits autophosphorylation of FGFR3 in a dose-dependent manner with IC50 of ~5 nM

FASCIN-G2 - Fascin Inhibitor. CAS# 1569076-11-4 yamine 3-²H₇)propan-2-yl]amino}ethyl)-17-oxa-3FASCIN G2, CAS No. 1569076 11 4, is a potent, selective and bioavailable small molecule that inhibits the actin bundling activity of fascin with Kd ~5 20 M. It specifically blocks filopodial formation, tumour cell migration and invasion in vitro. , FASCIN G2 showed very good in vivo efficacy in 4T1 mammary tumour metastasis model and in MDA MB 231 human breast tumour metastasis model. Product information CAS Number: 1569076 11 4 Molecular Weight: 385.

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