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InChi: InChI=1S/C16H24N2O3
Formula: C29H26N2O4
and irritation
It is also reported to block adrenergic α2 receptors in guinea pig vas deferens
selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 9 nM
JSH-23 - CAS# 749886-87-1 Catalog No.:M9452-10 InChi: InChI=1S/C16H24N2O3JSH 23 is a nuclear factor kappa B (NF B) nuclear translocation inhibitor. JSH 23 inhibits LPS and cytokine induced nuclear translocation of the p65 subunit of NF kB as analyzed by EMSA and western blot. JSH 23 treatment significantly reversed the nerve conduction and nerve blood flow deficits seen in diabetic animals. Reduction in mechanical pain threshold was also partially corrected by the treatment. Protein expression studies showed that nuclear
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