PC-766B Catalog No.:M22658-C 6-dimethylpyridin-3-yl}carbamate

6-dimethylpyridin-3-yl}carbamate

also known as CB1339 and X-Neu5Ac

InChiKey: PUHSRMSFDASMAE-UHFFFAOYSA-N

and decreases interleukin-1beta production by peritoneal macrophages

and tumor necrosis factor-α (TNF-α))

PC-766B Catalog No.:M22658-C 6-dimethylpyridin-3-yl}carbamatePC 766B is a macrolide antibiotic existed in anactinomycete strain SC 4710. PC 766B was active against Gram positive bacteria, and some fungi and yeasts, yet inactive against Gram negative bacteria. PC 766B exhibited potent cytotoxicity against murine tumor cell lines in vitro. The IC50 values against P388 leukemia and B16 melanoma were 0. 1 and 0. 5 ng ml, respectively . Intraperitoneal administration of PC 766B (0. 25mg kg day) showed in vivo