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Formula: C17H18Cl2N2O4S
Chemical Name: 3-(2-methylpropanoyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid
CAS Number: 579-75-9
InChiKey: RLUCYBFCLXANSO-BTJKTKAUSA-N
ClH/c1-6-4-8(20(2
8, 11, 14-Eicosatriynoic Acid 2iB Formula: C17H18Cl2N2O4S8,11,14 Eicosatriynoic Acid, as an inhibitor of prostaglandin, leukotriene biosynthesis, and arachidonic acid induced platelet aggregation, blocks human 12 lipoxygenase (12 LO), cyclooxygenase (COX), and 5 lipoxygenase (5 LO) with IC50 values of 0. 46 M, 14 M, and 25 M, respectively. Also, it inhibits the actions of slow reacting substance of anaphylaxis with an IC50 value of 10 M [1,2]. Lipoxygenases are found widely in fungi, plants, and animals in
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