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4-diazepane
orally active S1P1 agonist with an EC50 of 13
(2000) Bioorg Med Chem Lett
RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo
without influencing SIRT3 expression
LV-320 Size:10mg solid 4-diazepaneLV 320 is a potent and uncompetitive ATG4B inhibitor with an IC50 of 24. 5 M and a Kd of 16 M. LV 320 inhibits ATG4B enzymatic activity, blocks autophagic flux in cells, and is stable, non toxic and active in vivo. Product information CAS Number: 2449093 46 1 Molecular Weight: 520. 11 Formula: C29H26ClNO2S2 Chemical Name: 3 [({4 [(E) 2 (7 chloroquinolin 4 yl)ethenyl]phenyl}[(2 phenylethyl)sulfanyl]methyl)sulfanyl]propanoic acid Smiles:
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