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CGP 35348 Histone Methyltransferase COC1C=C2C(=NC=NC2=CC=1OCCCN1CCCCC1)N1CCN(CC1)C(=O)NC1C=CC(=CC=1)OC(C)C

SKU: 74513179949

4.8
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Description

COC1C=C2C(=NC=NC2=CC=1OCCCN1CCCCC1)N1CCN(CC1)C(=O)NC1C=CC(=CC=1)OC(C)C

5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-hydroxy-7-({[(methylsulfanyl)carbonyl]oxy}methyl)-1H

Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor

CP-724714 showed a favorable nonclinical toxicity profile with no apparent effects on cardiac tissue

IDX184 is a second generation

CGP 35348 Histone Methyltransferase COC1C=C2C(=NC=NC2=CC=1OCCCN1CCCCC1)N1CCN(CC1)C(=O)NC1C=CC(=CC=1)OC(C)CCGP 35348 is a selective antagonist of aminobutyric acidB (GABAB) receptor with IC50 value of 34 M . The GABAB receptor is a metabotropic transmembrane receptors for GABA that is linked via G protein to potassium channel. It stimulates the opening of K+ channel and hyperpolarize the neuron. CGP 35348 is a selective GABAB receptor antagonist that can penetrate the blood brain barrier. In rat cortex slices, CGP 35348 inhibited the potentiating effect of

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