ACT 178882 Catalog No.:M23965-C 2 nM in the β-arrestin

2 nM in the β-arrestin and Ca2+ release assay

InChi: InChI=1S/C26H42N6O12S2/c1-13(2)8-17(26(43)44)32-24(41)15(4-5-20(35)36)30-25(42)18(11-45)29-19(34)10-27-22(39)16(9-21(37)38)31-23(40)14(28-12-33)6-7-46-3/h12-18

10(6):1073-83

as an immunosuppressive drug

17-dodecahydro-1H-cyclopenta[a]phenanthrene-3

ACT 178882 Catalog No.:M23965-C 2 nM in the β-arrestinACT 178882 is a new Renin inhibitor with an IC50 of 1. 4 nM. Product information CAS Number: 1007392 69 9 Molecular Weight: 647. 03 Formula: C33H38Cl3N3O4 Chemical Name: (3R,4S) N {[2 chloro 5 (2 methoxyethyl)phenyl]methyl} N cyclopropyl 4 {6 [2 (2,6 dichloro 4 methylphenoxy)ethoxy]pyridin 3 yl}piperidine 3 carboxamide Smiles: CC1C=C(Cl)C(OCCOC2=CC=C(C=N2)[C@H]2CCNC[C@@H]2C(=O)N(CC2=CC(CCOC)=CC=C2Cl)C2CC2)=C(Cl)C=1 InChiKey: PGSRKJVMAOWDEC SXOMAYOGSA