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KW-2449 increases the percentage of cells in the G1 phase of the cell cycle and reciprocally reduces the percentage of cells in the S phase
is a farnesyltransferase inhibitor that is being investigated in patients 65 years of age and older with newly diagnosed acute myeloid leukemia (AML)
1438492-26-2
CAS Number: 1936422-33-1
Bardoxolone
Suplatast tosylate ustat KW-2449 increases the percentage ofSuplatast tosylate, also known as Suplatast tosilate, is a Th2 cytokine inhibitor which is used as an antiallergic drug. Often used in the treatment of Kimura's disease. Suplatast tosilate alleviates nasal symptoms through the suppression of nuclear factor of activated T cells mediated IL 9 gene expression in toluene 2, 4 diisocyanate sensitized rats. uplatast tosilate ameliorates airway hyperreactivity and inflammation through inhibition of the GATA3