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Discovery of highly potent
Smiles: CC(C)[C@H]1C(=O)N[C@@H](CC2=CNC3=CC=CC(=C23)N1C)CO
A drug for the treatment of type 2 diabetes mellitus[2]
It inhibits histone demethylase activity on H3K9me3 and induces apoptosis in LNCaP prostate cancer cells in vitro
compared to N2a cells
Larotrectinib Catalog No.:M7434-C Discovery of highly potentLarotrectinib (Vitrakvi, LOXO 101, ARRY 470) is an ATP competitive, oral administered and highly selective inhibitor of the tropomyosin related kinase (TRK) family receptors. Product information CAS Number: 1223403 58 4 Molecular Weight: 428. 44 Formula: C21H22F2N6O2 Synonym: Vitrakvi LOXO 101 ARRY 470 Chemical Name: (S) N (5 ((R) 2 (2,5 difluorophenyl)pyrrolidin 1 yl)pyrazolo[1,5 a]pyrimidin 3 yl) 3 hydroxypyrrolidine 1 carboxamide Smiles:
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