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4-dihydropyrido[3
October 2015 Oct 25:259-260
Formula: C17H22BrNO4
Chemical Name: (2S)-3-methyl-2-(N-{[2'-(1H-1
17-32)15-23(25)34/h7
Rocaglamide D012612 4-dihydropyrido[3Rocaglamide (Roc A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF B activation in T cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia. Product
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