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APC 366 de-O-amido-C8-NH2 hydrochloride 3-Hydroxyphenylacetic acid (3-HPAA) is a

SKU: 46078168309

4.2
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Description

3-Hydroxyphenylacetic acid (3-HPAA) is a phenolic acid mostly found in olive oil wastewater and an intestinal metabolite of the dietary flavonoid quercetin

Apigenin-7-glucoside provoks an increase of subG0/G1

SKF-86002 dihydrochloride inhibits lipopolysaccharide (LPS)-stimulate human monocyte IL-1 and TNF-α production (IC50 = 1 μM)

InChi: InChI=1S/C141H238N46O39S6

6-Hydroxy-DOPA (0~10 μM

APC 366 de-O-amido-C8-NH2 hydrochloride 3-Hydroxyphenylacetic acid (3-HPAA) is aAPC 366 is a selective and competitive inhibitor of tryptase [1, 2, 3]. After about 4 h of incubation with human tryptase, APC 366 showed an inhibitory potential with a Ki value of 530 nM and an IC50 value of 1400 240 nM . Tryptase is a mast cell serine protease. It had been implicated in the allergic asthma pathophysiology . It seemed that actions of tryptase were dependent on an intact catalytic site. APC 366 inhibited DNA synthesis and the

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