SPL-707 Catalog No.:M23926-C 000 nM for both A1

000 nM for both A1 and A2A AR and 3 nM for A2B AR subtype in CHO cells expressing recombinant human A1

decreases DSS-induced high levels of proinflammatory cytokines TNF-α

Chemical Name: (2S)-5-tert-butyl-3-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-2

and isoform-selective retinoic acid beta2 receptor agonist

Chemical Name: 2-(diethylamino)ethyl 2

SPL-707 Catalog No.:M23926-C 000 nM for both A1SPL 707 is an orally active, selective signal peptide peptidase like 2a (SPPL2a) inhibitor with an IC50 of 77 nM for hSPPL2a. SPL 707 inhibits secretase (IC50=6. 1 M) and SPP (IC50=3. 7 M). SPL 707 has the potential for autoimmune diseases research by targeting B cells and dendritic cells. Product information CAS Number: 2195361 33 0 Molecular Weight: 505. 54 Formula: C27H28FN5O4 Chemical Name: (2S) 2 cyclopropyl N [(9'S) 2',8' dioxo 3',7'