![5’-[(Desloratadine)methyl] Rupatadine-d8 Catalog No.:M26414-C Vasicinone is a quinazoline alkaloid](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M26414_1635977879.gif?v=1635977881)
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Vasicinone is a quinazoline alkaloid isolated from the Adhatoda vasica plant
3)28-18(23)4-10-24-12-14-26-16-17-27-15-13-25-11-7-20(5-8-21)6-9-22/h21-22H
It allosterically binds (Kd 10-30 nmol/L) to the regulatory Zn(2+) binding domain of HDAC4 that locks the protein in a conformation preventing HDAC4/N-CoR/HDAC3 complex formation
has a higher affinity for α1 (Ki = 77 nM) and 5-HT2 (Ki = 25 nM) binding sites
and reducing bleeding in clinical trials
5’-[(Desloratadine)methyl] Rupatadine-d8 Catalog No.:M26414-C Vasicinone is a quinazoline alkaloidProduct information CAS Number: 1794669 33 2 Molecular Weight: 732. 81 Formula: C45H43Cl2N5 Chemical Name: 13 chloro 2 [1 ({5 [(4 {13 chloro 4 azatricyclo[9. 4. 0. 0,]pentadeca 1(15),3,5,7,11,13 hexaen 2 ylidene}(2,2,6,6 H)piperidin 1 yl)methyl]pyridin 3 yl}methyl)(2,2,6,6 H)piperidin 4 ylidene] 4 azatricyclo[9. 4. 0. 0,]pentadeca 1(15),3,5,7,11,13 hexaene Smiles:
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